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glun2a subunit  (Alomone Labs)


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    Structured Review

    Alomone Labs glun2a subunit
    Glun2a Subunit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 29 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glun2a+subunit/Anti-NMDAR2A+(GluN2A)+(extracellular)+Antibody/pm40294743-234-4-9
    Average 94 stars, based on 29 article reviews
    glun2a subunit - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Next-Generation Sequencing:

    Article Title: Glycine-gated extrasynaptic NMDARs activated during glutamate spillover drive burst firing in nigral dopamine neurons.
    Article Snippet: Burst firing in substantia nigra pars compacta dopamine neurons is a critical biomarker temporally associated to movement initiation.. This phasic change is generated by the tonic activation of NMDARs but the respective role of synaptic versus extrasynaptic NMDARs in the ignition of a burst and what is their level of activation remains unknown.. Using ex vivo electrophysiological recordings from adolescent rats, we demonstrate that extrasynaptic NMDARs are the primary driver of burst firing.

    Article Title: Co-agonist glycine controls the occurrence of bursts by activating extrasynaptic NMDARs in nigral dopamine neurons
    Article Snippet: .. Primary antibodies were against GluN2A subunit (rabbit anti-GluN2A 1:200, Alomone AGC-002) combined to mouse anti-TH (1:1000, Immunostar 22941, Abcam, UK), or GluN2B subunit (rabbit anti-GluN2B 1:200, Alomone AGC-003) with mouse anti-TH or GluN2D subunit (rabbit anti-GluN2D 1:200, Alomone AGC-020) with mouse anti-TH in 5% NGS in PBS and 0.1% Triton X-100 overnight at 4 °C. .. After rinsing, slices were incubated with secondary antibodies (goat anti-mouse alexa Fluor 568 1:500, Invitrogen A-11004 and goat anti-rabbit Alexa Fluor 488 1:400, Invitrogen A-11011) in PBS with 0.1% Triton X-100 for 2 hours at room temperature.



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